Patients are asking about Coenzyme Q10
... from the Cleve Clin J Med. 2010 Jul;77(7):435-42.
"In some clinical trials, coenzyme Q10 supplements significantly lowered diastolic and systolic blood pressure.
"Statins may lower coenzyme Q10 serum levels, and some investigators have evaluated the relationship between coenzyme Q10 deficiency and statin-related myalgia, but more evidence is needed to support the use of coenzyme Q10 supplements to prevent or treat myalgia.
"Coenzyme Q10 supplementation appears to be relatively safe. Most clinical trials have not reported significant side effects that necessitated stopping therapy. Gastrointestinal effects include abdominal discomfort, nausea, vomiting, diarrhea, and anorexia. Allergic rash and headache have also been reported.
"A typical daily dose of coenzyme Q10 for treating hypertension is 120 to 200 mg, usually given orally in two divided doses.
"For statin-induced myopathy, 100 to 200 mg orally daily has been used.
Coenzyme Q10 is given in divided doses to enhance its absorption and to minimize gastrointestinal effects. Taking it with a fatty meal may also increase its absorption."